蓋膜( がいまく、英:tectorial membrane )

 

頚部にも同じ名称の膜が存在する。

 

以下は「Wikipedia」の解説文の一部を箇条書きにしたものになる。

 ・基底板と同じで細胞を内包しない膜

 ・3部構成 ⇒イラスト解説

   1.ラセン板縁部:ラセン板縁の上部に位置する最も薄い部分

   2.中間部:だいたい内ラセン溝の上部にあたる部分

   3.辺縁部:内・外有毛細胞の上部にあたる最も厚い部分(中間部と辺縁部の境界はヘンゼン線(条))

 ・ゲル状で97%は水分

  (乾燥重量での内訳はコラーゲン(50%)、非コラーゲン糖タンパク質(25%)、糖タンパク質 (25%) 

 

 

蓋膜(拡大)
蝸牛(断面)
蝸牛(断面)

 

以下は「Wikipedia」の解説文となる。

The tectoria membrane (TM) is one of two acellular membranes in the cochlea of the inner ear, the other being the basilar membrane (BM). "Tectorial" in anatomy means forming a cover. The TM is located above the spiral limbus and the spiral organ of Corti and extends along the longitudinal length of the cochlea parallel to the BM.

 Radially the TM is divided into three zones, the limbal, middle and marginal zones. Of these the limbal zone is the thinnest (transversally) and overlies the auditory teeth of Huschke with its inside edge attached to the spiral limbus. The marginal zone is the thickest (transversally) and is divided from the middle zone by Hensen's Stripe. It overlies the sensory inner hair cells and electrically-motile outer hair cells of the organ of Corti and during acoustic stimulation stimulates the inner hair cells through fluid coupling, and the outer hair cells via direct connection to their tallest stereocilia.

【 語 句 】

・acellular:無細胞の ・cochlea:蝸牛 ・inner ear:内耳 ・basilar membrane:基底膜 ・spiral limbus:ラセン板縁 ・spiral organ of Corti:コルチ器 ・radially:放射状に ・limbal:辺縁の? ・auditory teeth of Huschke:フシュケの聴歯 ・Hensen's Stripe:ヘンゼン線(条) ・inner hair cells:内有毛細胞 ・outer hair cells:外有毛細胞 ・acoustic stimulatio:音響刺激試験 ・fluid coupling:流体継手 ・stereocilia:不動毛


【Structure】

 The TM is a gel-like structure containing 97% water. Its dry weight is composed of collagen (50%), non-collagenous glycoproteins (25%) and proteoglycans (25%). Three inner-ear specific glycoproteins are expressed in the TM, α-tectorin, β-tectorin and otogelin. Of these proteins α-tectorin and β-tectorin form the striated sheet matrix that regularly organises the collagen fibres. Due to the increased structural complexity of the TM relative to other acellular gels (such as the otolithic membranes), its mechanical properties are consequently significantly more complex. They have been experimentally shown to be radially and longitudinally anisotropic and to exhibit viscoelastic properties.

【 語 句 】

・gel-like:ゲル状の ・glycoprotein:糖タンパク質 ・proteoglycan:プロテオグリカン ・otogelin:オトゲリン ・striated:筋のある、線状の ・otolithic membrane:耳石膜 ・consequently:結果的に ・experimentally:実験的に ・radially:放射状に ・ longitudinally:縦方向に ・anisotropic:異方性の ・exhibit:陳列する、示す ・viscoelastic:粘弾性の ・property:特性

【Function】

 The mechanical role of the tectorial membrane in hearing is yet to be fully understood, and traditionally was neglected or downplayed in many models of the cochlea. However, recent genetic , mechanical and mathematical studies have highlighted the importance of the TM for healthy auditory function in mammals. Mice that lack expression of individual glycoproteins exhibit hearing abnormalities, including, most notably, enhanced frequency selectivity in Tecb−/− mice, which lack expression of β-tectorin. In vitro investigations of the mechanical properties of the TM have demonstrated the ability of isolated sections of TM to support travelling waves at acoustically relevant frequencies. This raises the possibility that the TM may be involved in the longitudinal propagation of energy in the intact cochlea. MIT research correlates the TM with the ability of the human ear to hear faint noises.
 The TM influences inner ear sensory cells by storing calcium ions. When calcium store is depleted by loud sounds or by the introduction of calcium chelators, the responses of the sensory cells decrease. When tectorial membrane calcium is restored, sensory cell function returns.

【 語 句 】

・neglect:無視する ・downplay:軽視する ・genetic:遺伝学の ・notably:著しく、明白に ・enhance:増す ・frequency selectivity:周波数選択 ・travelling waves:進行波 ・relevant:適切な、関連のある ・propagation:伝播 ・intact:手が付けられていない ・correlate:互いに関係がある

 

■ 写真やイラストを掲載しているサイト ■

イラストや写真を掲載しているサイト-Ⅰ

イラストや写真を掲載しているサイト-Ⅱ

イラストや写真を掲載しているサイト-Ⅲ

イラストや写真を掲載しているサイト-Ⅳ