・レチクリン線維とも。
・「基底膜の裏打ちとして存在し(基底膜と膠原線維を結び付ける)、それぞれの細胞を機械的に支持」(oralstudio)
以下は「Wikipedia」の解説文となる。
Reticular fibers, reticular fibres or reticulin is a type of fiber in connective tissue composed of type III collagen secreted by reticular cells. Reticular fibers crosslink to form a fine meshwork (reticulin). This network acts as a supporting mesh in soft tissues such as liver, bone marrow, and the tissues and organs of the lymphatic system.
【History】
The term reticulin was coined in 1892 by M. Siegfried.
Today, the term reticulin or reticular fiber is restricted to referring to fibers composed of type III collagen. However, during the pre-molecular era, there was confusion in the use of the term reticulin, which was used to describe two structures:
- the argyrophilic (silver staining) fibrous structures present in basement membranes
- histologically similar fibers present in developing connective tissue.
【 語 句 】
・connective tissue: ・secrete:・reticular cell: ・crosslink:架橋する ・bone merrow: ・lymphatic system: ・coin:造り出す ・argyrophilic:銀親和性の ・basement membrane:基底膜 ・histologically:組織学的に
【Structure】
Reticular fiber is composed of one or more types of very thin and delicately woven strands of type III collagen. These strands build a highly ordered cellular network and provide a supporting network. Many of these types of collagen have been combined with carbohydrate. Thus, they react with silver stains and with periodic acid-Schiff reagent but are not demonstrated with ordinary histological stains such as those using hematoxylin. The 1953 Science article mentioned above concluded that the reticular and regular collagenous materials contains the same four sugars – galactose, glucose, mannose, and fucose – but in a much greater concentration in the reticular than in the collagenous material.
In a 1993 paper, the reticular fibers of the capillary sheath and splenic cord were studied and compared in the pig spleen by transmission electron microscopy. This paper attempted to reveal their components and the presence of sialic acid in the amorphous ground substance. Collagen fibrils, , microfibrils, nerve fibers, and smooth muscle cells were observed in the reticular fibers of the splenic cord. On the other hand, only microfibrils were recognized in the reticular fibers of the capillary sheath. The binding of LFA lectin to the splenic cord was stronger than the capillary sheath. These findings suggested that the reticular fibers of the splenic cord include multiple functional elements and might perform an important role during contraction or dilation of the spleen. On the other hand, the reticular fiber of the capillary sheath resembled the basement membrane of the capillary in its components.
Because of their affinity for silver salts, these fibers are called argyrophilic.
【 語 句 】
・strand:要素 ・carbohydrate:炭水化物 ・silver stain:銀汚染 ・periodic acid-Schiff:過ヨウ素酸シッフ反応 ・reagent:試薬 ・hematoxylin:ヘマトキシリン ・fucose: ・capillary:毛管の ・sheath:鞘 ・splenic cord:脾索 ・spleen: ・transmission electron microscopy:透過型電子顕微鏡 ・sialic acid:シアル酸 ・amorphous:組織のない ・ground substance:基底質 ・fibril:原繊維 ・microfibril:細毛繊維 ・dilation:拡大 ・resemble:似ている ・affinity:類似性 ・silver salt:銀塩 ・argyrophilic:銀親和性の
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